Stearates have various uses in the pharmaceutical industry. It functions as a human metabolite, a plant metabolite, and a Saccharomyces cerevisiae metabolite. It is a long-chain fatty acid anion, a straight-chain saturated fatty acid anion, an 18:0 fatty acid anion, and a 2-saturated fatty acid anion.
Octadecanoic acid is a fatty acid anion 18:0 and is the conjugate base of octadecanoic acid (stearic acid). Stearates have various uses in the pharmaceutical industry. It functions as a human metabolite, a plant metabolite, and a Saccharomyces cerevisiae metabolite. It is a long-chain fatty acid anion, a straight-chain saturated fatty acid anion, an 18:0 fatty acid anion, and a 2-saturated fatty acid anion. It is the conjugate base of octadecanoic acid.
Salts and esters of 18-carbon saturated monocarboxylic acid-stearic acid.
Stearate is modeled into this channel such that the carbon atom at the ?9 position is close to one of the iron ions and also close to a small pocket.
Due to its low surface area, stearic acid is used in concentrations of 1%–3% w/w. Magnesium stearate at a concentration of 0.25% w/w has been reported to soften tablets made with pregelatinized starch and may affect tablet strength and dissolution, so stearic acid is the lubricant of choice for pregelatinized starch agent. Starch undergoes plastic deformation during tableting and therefore has a high sensitivity to the concentration of magnesium stearate. Furthermore, stearic acid protected the drug (aspirin) from degradation, although magnesium stearate accelerated the degradation of aspirin, as reported by Fouda et al. (Fouda, Mady, & El-Azab, 1998).
The stearoyl-CoA desaturase (also known as delta-9 desaturase) system rapidly desaturates palmitate (C16:0) and stearate (C18:0) to monounsaturated palmitoleic acid ( C16:1) and oleic acid (C18:1) (Figure 2). Stearoyl-CoA desaturase exists in multiple isoforms derived from different genes.
There are several forms of erythromycin, including ethyl succinate and acetate and stearate for oral administration. However, the estolate form is only available as a suspension.
This amphiphile is soap and other detergents. Sodium stearate is thus a typical soap: CH3(CH2)16COO? Na+ – the long paraffin tail is a very distinctive feature. There are several other types of detergents, most are designed to be more "soluble" in water than soap, and are designed in some way to increase the efficiency of the interaction.
Preformed vitamin A (mainly retinyl palmitate and small amounts of other retinyl esters including stearate, myristate, and oleate) and very small amounts of provitamin A procarotenoids are obtained from animal sources of. Particularly rich sources of preformed vitamin A include liver, whole milk, egg yolks and fish.